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Infusion of Donor T-Cells Boosts Survival Chances in Leukemia

image Fred Hutchinson Cancer Research Center researchers have managed to infuse large numbers of donor T-cells specific for a key anti-leukemic antigen to prolong survival in high-risk and relapsed leukemia patients after stem cell transplantation. Both the stem cells for transplant and the T-cells came from the same matched donors.Reporting results of a pilot clinical trial in the Feb. 27 issue of the journal iScience Translational Medicine/i, researchers describe the use of T-cells ...
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Surprising New Influence on Cancer Genes Found By Scientists

image Small stretches of DNA in the human genome are known as "pseudogenes." They are called so because, while their sequences are nearly identical to those of various genes, they have long been thought to be non-coding "junk" DNA. But now, a new study led by scientists at The Scripps Research Institute (TSRI) shows how pseudogenes can regulate the activity of a cancer-related gene called PTEN. The study also shows that pseudogenes can be targeted to control PTEN's activity. P...
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Rise in Incidence of Advanced Breast Cancer Among Younger Women Revealed in Study

image A small but statistically significant increase in the incidence of advanced breast cancer for women 25 to 39 years of age is seen in an analysis of breast cancer trends in the U.S. The study appearing in the February 27 issue of iJAMA/i does not find a corresponding increase in older women. "In the United States, breast cancer is the most common malignant tumor in adolescent and young adult women 15 to 39 years of age, accounting for 14 percent of all cancer in men and women in...
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Advanced Breast Cancer on Rise Among Younger Women

image In the United States, the incidence of advanced breast cancer among women aged 25 to 39 has increased over the past thirty years, finds study. Published in the Journal of the American Medical Association, the study found that cases increased from 1.53 per 100,000 in 1976 to 2.90 per 100,000 in 2009. According to the researchers, that represents an average compounded increase of 2.07 percent per year over the 34-year period. While that is a relatively sm...
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Lung Cancer Screening Could Save 12,000 Deaths Every Year in the US

image A new study published in the journal Cancer reveals that around 12,000 deaths caused by lung cancer could be avoided every year in the United States by screening for the disease with the help of low-dose computed tomography (LDCT). Despite substantial decreases in smoking prevalence, there are still 43 million Americans who are current smokers. If these smokers continue to smoke, half of them will die of smoking-related diseases including lung cancer; however, detecting lung cancer a...
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Honey may Help Fight Cancer

image Manuka honey could inhibit the growth of cancer cell types including breast, skin, and colon cancer, say researchers. Though the honey, obtained from nectar collected by honey bees from manuka trees found in New Zealand, has been recognised for its anti-bacterial and wound healing properties for many years, it has never been investigated for its potential effects on cancer cells, said a UAE University official. He said that the ground-breaking discovery provides st...
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General Mechanism That Accelerates Tumor Development Discovered

image Scientists have discovered a mechanism controlled by the CPEB1 protein that affects more than 200 genes related to cell proliferation and tumor progression. The mechanism, which was discovered using Hodgkin lymphoma cells, has been proposed as a general regulatory system that enhances the spread of cancer. The researchers describe that CPEB1 shortens a highly specific region of RNAs (RNAs are the molecules that carry gene information for protein synthesis). This region holds mos...
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Cutting-Edge Technology for Cancer Detection in Gurgaon Hospital

image A cutting-edge imaging technology for early cancer detection was introduced at a private hospital in Gurgaon on Friday. The technology works on a combination of m-Dixon and diffusion weighted imaging with background suppression (DWIBS). While m-Dixon is an established Magnetic Resonance Imaging Technique for liver imaging that provides four sets of images: water-only, fat-only, and phase images (IP and OP), diffusion weighted imaging with background is used for whole-body imaging. ...
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Head and Neck Cancer Molecular Tumor Subtypes Highlighted in UNC-Led Study

image Except an association with the human papillomavirus, no validated molecular profile of head and neck squamous cell carcinoma (HNSCC) has been established despite the fact that it is the seventh most common form of cancer in the United States. By analyzing data from DNA microarrays, a UNC-led team has completed a study that confirms the presence of four molecular classes of the disease and extends previous results by suggesting that there may be an underlying connection between the mo...
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Natural, Nontoxic Product Could Increase Life Expectancy in Prostate Cancer Patients

image Researchers have found that genistein-combined polysaccharide, or GCP, a natural, nontoxic product which is commercially available in health stores, could help increase the life expectancy of certain prostate cancer patients. The research that was conducted in prostate cancer cells and in mice focused on GCP, a proprietary extract cultured from soybeans and shiitake mushrooms and marketed by Amino-Up of Sapporo, Japan. Men with prostate cancer that has spread to other par...
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