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Routine Blood Test May Predict Survival in Patients With Aggressive Skin Cancer

image A routine blood test may help predict survival in patients with an aggressive form of skin cancer known as Merkel cell carcinoma, reveal new findings by Fox Chase Cancer Center researchers. The results will be presented on Wednesday, October 31 at the American Society for Radiation Oncology's 54th Annual Meeting. "With such a fast-growing cancer, we get one question a lot: 'how long do I have?'," says Matthew Johnson, MD, a resident physician in the Department of Radiation Oncology a...
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Scientists Find Biomarker That Can Improve Breast Cancer Therapy

image A molecular 'flag' in women with breast cancer who do not respond or have become resistant to the hormone drug tamoxifen has been identified by researchers. Tamoxifen - used alongside traditional chemotherapy and radiotherapy - blocks the female hormone oestrogen that, in certain breast cancers, is required by the tumour to grow; it has been shown to improve cancer survival rates by up to one third. However, about one third of patients with the appropriate type of breast ...
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Drop in Testosterone Could Signal Prostate Cancer Recurrence

image Drop in testosterone following radiation therapy for prostate cancer is linked to recurrence of prostate cancer, finds recent research. Specifically, men whose testosterone fell following various forms of radiation therapy were more likely to experience an increase in prostate-specific antigen (PSA)-often the first indication the cancer has recurred. "The men who had a decrease in testosterone also appear to be the men more likely to see an increase in PSA after tr...
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Scientists Explore Link Between Age and Rectal Cancer Spread

image According to a recent study, rectal cancer is more likely to spread to the lymph nodes in younger patients. The results-which are the first of their kind-suggest that doctors should search for spreading more aggressively in these patients. Once rectal cancer has spread to the lymph nodes, it is more likely to return to the pelvis following surgery. Administering chemotherapy and radiation before surgery reduces that risk, so before the procedure doctors typically perform a scan-...
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Regular Exercise may Help Stave Off Depression in Women With Breast Cancer

image A new study conducted by researchers at Strathclyde and Dundee universities has found that regular exercise may be more beneficial to women who are diagnosed with breast cancer as it reduces the risk of depression and improves the quality of life in the long run. The study was funded by Macmillan Cancer Support and involved 203 women diagnosed with breast cancer who had taken part in the 12-week supervised group exercise program during treatment for early-stage breast cancer. ...
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A New Type of T Cell to Target Melanoma Exposed By Mouse Model

image It is a known fact that cancers arise in the body all the time. They are mostly nipped in the bud by the immune response, not least by its T cells, which detect telltale molecular markers-or antigens-on cancer cells and destroy them before they grow into tumors. For their part, cancer cells, evolve constantly to evade such assassination. Those that succeed become full-blown malignancies. Yet, given the right sort of help, the immune system can destroy even these entrenched tumors.
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Benefit from Avastin in Bowel Cancer Could be Predicted by Protein Levels

image Until now there has been no way of predicting the benefit of Avastin, or Bevacizumab, in bowel cancer although it has been shown to increase survival in around ten to 15 per cent of patients with the condition. Avastin works by targeting and blocking the VEGF-A protein, two major forms of which are VEGF165 and VEGF165b. VEGF165 helps cancers to grow new blood vessels, so they can get food and oxygen from the blood - all cancers need a blood supply to be able to survive ...
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World’s First Online Prostate Cancer Database Allows Patients to Track Their Disease and Avoid Complications

image Prostate cancer patients can now track their disease online and avoid complications due to overtreatment following the launch of National Proactive Surveillance Network, the first ever online medical database about prostate cancer. A project of the Prostate Cancer Foundation, the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute and Johns Hopkins, the National Proactive Surveillance Network will allow men diagnosed with slow-growing forms of the disease to track their disea...
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Amino Acids Present in the Ends of Chromosomes may be Targeted by New Cancer Drugs

image Researchers at University of Colorado Boulder have identified a new target present at the ends of the chromosomes that can be exploited to develop new anti-cancer drugs, a new study published in the journal Nature reveals. Researchers in the two scientists' laboratories collaborated to find a patch of amino acids that, if blocked by a drug docked onto the chromosome end at this location, may prevent cancerous cells from reproducing. The amino acids at this site are called the "TEL pa...
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Cancer Patients in Advanced Stages of Their Disease Overestimate Chemotherapy’s Ability to Cure

image A new study by Dana-Farber Cancer Institute researchers has found that lung and colorectal cancer patients who are in advanced stages of the disease tend to be more optimistic about the chances of their disease being cured by chemotherapy. The study, published in the Oct. 25 issue of the iNew England Journal of Medicine/i, found that 69 percent of patients with advanced lung cancer and 81 percent of patients with advanced colorectal cancer did not understand that the chemotherapy...
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