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Cancer Progression Predicted By Tumor Cells’ Inner Workings

image Researchers using a new assay method to study tumor cells have found evidence of clonal evolution in chronic lymphocytic leukemia (CLL). The researchers are from the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center. The assay method distinguishes features of leukemia cells that indicate whether the disease will be aggressive or slow-moving, a key factor in when and how patients are treated.
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Use of Diagnostic Imaging Among Stage IV Cancer Patients on the Rise

image The use of diagnostic imaging in Medicare patients with stage IV cancer has increased faster than among those with early-stage (stages I and II) disease, according to a study published July 30 in the iJournal of the National Cancer Institute/i. The costs of diagnostic imaging have increased more rapidly than the overall costs of cancer care, making diagnostic imaging the fastest-growing division of Medicare-reimbursed services. The net costs of cancer care are the highest in the ...
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Absence of PSA Testing Could See Number of Advanced Prostate Cancer Cases Rise by Three Times

image Underlining the importance of PSA (prostate specific antigen) testing, a new study has found that the number of cases with advanced prostate cancer that has spread to other parts of the disease could rise by three times without such screening method. PSA testing has come under fire recently as a potentially ineffective screen for prostate cancer. Last year a government panel reviewed the available evidence and concluded that PSA testing has little or no benefit and that doctors are f...
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Study Finds Surgical Patient Safety Program Lowers SSIs by One-Third Following Colorectal Operations

image A study published in the August issue of the IJournal of the American College of Surgeons/I has revealed that a surgical patient safety program that combines three components reduces surgical site infections (SSIs) by 33 percent in patients who undergo colorectal procedures. The three components include accurate outcome measurement, support of hospital leadership, and engaging frontline providers.
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Skin Cancer Gene Identified by Scientists

image The world's largest study of skin cancer genetics by scientists in Australia and the United States has led to the discovery of a mutant gene responsible for almost one in 10 melanomas. During the study, researchers analyzed every gene in 147 melanomas and they discovered the same mutation was present in almost 10 per cent of them. "Because it is a mutation that is an accelerator of tumor growth and development, it lends itself very well to drug targeting to come up with new thera...
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Teen’s Artificial ‘Brain’ Helps Detect Breast Cancer

image A 17-year-old US teen has won the grand prize at the annual Google Science Fair for her cloud-based computer program that makes breast cancer detection less invasive. In the science talent competition for kids aged 13 to 18, which was held this month in Palo Alto, California, Brittany Wenger created computer programs coded to think like the human brain and then used them to locate mass malignancy in breast tissue samples. She called it the "Global Neural Network Cloud Ser...
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Focusing on Patients With NSCLC, Scientists Hunting For Second-Line Defence

image Concerning lung cancer, people who successfully benefit from drugs like erlotinib will certainly develop drug resistance. This is heralded by cancer growth and increasing tumor-related symptoms. Now scientists are investigating a second line of defense by studying the use of the novel AKT inhibitor MK-2206 in combination with erlotinib for patients whose benefit from erlotinib has begun to wane. Results of a Phase II trial will be presented during the 5th Latin American Conference on Lung Cancer...
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Treatment of Choice for Metastatic Melanoma Questioned

image The treatment of choice to date for patients with stage IV metastatic melanoma has been the administration of high-doses of interleukin-2 (IL-2). An article published in the current issue of iCancer Biotherapy and Radiopharmaceuticals/i, a peer-reviewed journal from Mary Ann Liebert, Inc. (a target="_blank" href="http:www.liebertpub.com"http:www.liebertpub.com/a), explores whether or not this regimen is still the most effective. The article is available free online at the ...
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Study Finds Men With Prostate Cancer More Likely to Die from Other Causes

image A new study from Harvard School of Public Health (HSPH) says that men diagnosed with prostate cancer are less likely to die from the disease than from other conditions such as heart disease. It is the largest study to date that looks at causes of death among men with prostate cancer, and suggests that encouraging healthy lifestyle changes should play an important role in prostate cancer management. "Our results are relevant for several million men living with prostate c...
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Genetic Cause of Most Lethal Brain Tumor Discovered

image Recent study pinpoints the genetic cause of glioblastoma - the most common and aggressive form of primary brain cancer. The study also found that drugs that target the protein produced by this genetic aberration can dramatically slow the growth of glioblastomas in mice. The findings were published today in the online edition of the journal iScience/i. "Our findings are doubly important," said study leader Antonio Iavarone, MD, professor of pathology and neurology at CUMC, ...
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