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Mutant Kras Compels Pancreatic Cancer Upkeep by Metabolic Pathways

image A genetic mutation coercing the launch of pancreatic cancer also fudges metabolic pathways to support tumour growth and progression, scientists report in the journal iCell/i. This newly discovered role for the Kras oncogene opens up a new category of potential targets for thwarting the influential mutation, which has proved difficult to attack directly, said study co-lead author Haoqiang Ying, Ph.D., instructor in The University of Texas MD Anderson Cancer Center Department of Ge...
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115 Proteins That may Help Formulate New Generation Anti-Cancer Drugs Identified

image Researchers have identified 115 proteins via computer simulation that could be highly relevant to treat colo-rectal cancer. This is because these proteins would make it possible to define the strategy to design new generation anti-cancer drugs. The research was conducted by researchers from the Research Programme in Biomedical Informatics (GRIB) from the IMIM (Hospital del Mar Research Institute) and the Pompeu Fabra University (UPF).
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New Tool That Accurately Diagnose Prostate Cancer Found

image A team of researchers have found a more accurate test that not only help to diagnose whether a patient has prostate cancer but also how aggressive it is. "That's really what is unique and exciting about our new discovery," said associate professor Qun "Treen" Huo, the lead investigator on the project. "Our nanoparticles not only seek out a chemical reaction that is specific to prostate cancer, they can also tell us how aggressive the cancerous cells are likely to be, which can give d...
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Oral Cancer Diagnosis Could be Speeded Up Through New Portable Probe

image Researchers at University of Texas, Austin, have developed a new portable mini microscope that promises to speed up the time needed to diagnose oral cancer. The probe, around 20 cm long and one cm wide at its tip, could be used to diagnose oral cancer in real-time or as a surgical guidance tool. Dentists could also use it to screen for early-stage cancer cells. researchers said. Oral cancers have traditionally been diagnosed by biopsy, in which a sample of tissue from th...
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Study Identifies Oral Cancer Causing-chemical in Smokeless Tobacco

image A research in the US has, for the first time, identified a specific oral cancer-causing chemical in smokeless tobacco products, such as 'gutka' and similar products. Dr. Silvia Balbo of the Masonic Cancer Center at the University of Minnesota in Minneapolis, US, found after a study on rats that smokeless tobacco products contain a strong oral carcinogen -- a chemical called (S)-N'-nitrosonornicotine, or (S)-NNN. Dr. K.R. Thankappan, professor and head, Achutha Menon Centr...
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Lung Cancer Risk Influenced by Genetic Variants and Tobacco Exposure

image Lung cancer risk is largely mediated by level of tobacco exposure as there is an association between the rs1051730-rs16969968 genotype and objective measures of tobacco exposure. These are the findings of a study published April 25 in the iJournal of the National Cancer Institute/i. The rs1051730-rs16969968 genotype is known to be associated with heaviness of smoking, lung cancer risk, and other smoking-related outcomes. Prior studies have generally depended on self-reported smok...
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Eating Healthy and Exercising Regularly can Prevent Cancer Relapse

image Trying to lead a healthy lifestyle by exercising and eating well when being diagnosed with cancer can have hidden benefits after a new study found that such a habit could prevent the cancer from coming back. The American Cancer Society issued new guidelines stating that doctors should encourage cancer patients to eat well, exercise and to slim down if they are overweight. The guidelines have been based on more than 100 studies conducted in the past five years with majority of ...
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Breast Cancer Survivors Can Get Better Quality Of Life Letting Go Of Old Goals

image Breast cancer survivors who chose and were able to let go of former goals and set fresh ones explained an improved overall well-being, discovered researchers. Once the self-imposed pressure of now unrealistic goals was removed, individuals' quality of life improved, as did their level of physical activity. Carsten Wrosch of Concordia University's Department of Psychology and Centre for Research in Human Development and Catherine Sabiston of McGill's Department of Kinesiolo...
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Risk of Liver Cancer High Among Those With Family History

image The risk of developing hepatocellular carcinomas (HCC) is high among those who have a definite history of liver cancer in their families. The study also showed 70-fold elevated risk of HCC in those with liver cancer in the family and markers for hepatitis B (HBV) or hepatitis C (HCV). Liver cancer ranks sixth in incidence and the third cause of mortality worldwide. According to the World Health Organization (WHO) liver cancer was responsible for 700,000 deaths...
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Anxiety Boosts Cancer Severity

image Anxiety-prone mice developed more severe cancer, shows study. The study, to be published online April 25 in IPLoS ONE, /Ifound that after hairless mice were dosed with ultraviolet rays, the nervous ones - with a penchant for reticence and risk aversion - developed more tumors and invasive cancer. Consistent anxiety also came with sensitivity to chronic stress and a dampened immune system. Though other researchers have already linked chronic stress to higher risks for cancer ...
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