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New Gene Linked To Breast Cancer Risk Identified

image Mutations in a gene called XRCC2 may lead to increased breast cancer risk, according to a new study. The study looked at families that have a history of the disease but do not have mutations in the currently known breast cancer susceptibility genes. Sean Tavtigian, Ph.D., a Huntsman Cancer Institute (HCI) investigator and associate professor in the Department of Oncological Sciences at the University of Utah (U of U) is one of three co-principal investigators on the study...
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CT Scans More Effective Than Traditional Methods In Detecting Lung Cancer

image CT scans are more effective in detecting lung cancer, than the traditional methods, at identifying aggressive lung cancers in their most treatable stages. The data, published online March 27 in the journal IRadiology/I, demonstrate that lung cancers found through annual CT screening are similar to those found in routine practice, both in terms of tumor growth rates and cell-type distribution. In fact, the report showed that 79 percent of the cases diagnosed through annual repeat ...
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Research Identifies Mechanism Behind Invasive Breast Cancer

image A new study has identified a key mechanism that causes breast cancer to spread. The research, published by Cell Press on March 30th in the journal IMolecular Cell/I, enhances our knowledge about the signals that drive cancer metastasis and identifies new therapeutic targets for a lethal form of invasive breast cancer that is notoriously resistant to treatment. Amplification of the gene for ErbB2 has been linked with aggressive forms of breast cancer and is associated ...
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Pancreatic Cancer Patients Find Electrical Pulse Treatment Promising

image Ray of hope for people with inoperable locally advanced pancreatic cancer (LAPC) according to results of a study presented at the Society of Interventional Radiology's 37th Annual Scientific Meeting in San Francisco, California. A new procedure called irreversible electroporation or IRE uses microsecond electrical pulses to force open and destroy tumor cells around a vast and delicate network of blood vessels of the pancreas. The technique has been successful in treating primary and metastatic ...
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Cancer Deaths in US Continue to Fall

image Deaths due to cancer in the United States have continued to decline over the past decade, according to a yearly report on US cancer statistics released Wednesday. Trends in death rates from cancer declined an average of 1.7 percent per year among men and 1.3 percent among women and children from 1998 to 2008, the latest period studied, said the Annual Report to the Nation on the Status of Cancer. New cancer diagnoses also decreased less than one percent per year from 1996...
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Radiation Exposure Reduced by Lower Dosage CT-Guided Lung Biopsy Protocol

image Radiation exposure is significantly reduced by new guidelines for CT-guided biopsies of lung nodules, thus allowing individuals to benefit from the procedure. This research is being presented at the Society of Interventional Radiology's 37th Annual Scientific Meeting in San Francisco, Calif. "The published early results of a trial using computed tomography to detect lung nodules demonstrated that screening with low-dose CT reduced mortality from lung cancer by 20 percent...
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Detecting Cancer in Early Stages

image The mechanism which causes normal cells to develop into cancer has been uncovered by research from Queen Mary, University of London. The study, published in the online journal IPLoS ONE/I today (26 March), investigated the role of the notorious cancer gene FOXM1. Lead investigator Dr Muy-Teck Teh from Queen Mary, University of London, said the team found that the FOXM1 gene "brain washes" normal cells so they adopt a 'memory' pattern similar to cancer cells. ...
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Obstacles to Cancer Prevention Strategies

image More than fifty percent of all cancer is preventable, and society has the knowledge to act on this information today and lessen the cancer burden, said Washington University public health researchers at the Siteman Cancer Center in St. Louis. In a review article published in iScience Translational Medicine/i March 28, the investigators outline obstacles they say stand in the way of making a huge dent in the cancer burden in the United States and around the world. "We ...
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Study Says Half of All Cancers are Preventable

image A recent study says that half of all cancers are preventable if people adopt healthier behaviors. Smoking is blamed for a third of all US cancer cases and being overweight leads to another 20 percent of the deadly burden that costs the United States some (Dollor) 226 billion per year in health care and lost productivity. For instance, up to three quarters of US lung cancer cases could be avoided if people did not smoke, said the review article in the US journal Science Transla...
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Breast Cancer Tumors and Chemotherapy Treatment

image A recent research states that some breast cancer tumors may be resistant to a common chemotherapy treatment. Principal investigator Ing Swie Goping and her team discovered some breast cancer tumours had low levels of certain genes, and that those tumours didn't respond well to taxane chemotherapy, a common treatment used in breast cancer. "These tumours didn't shrink and were resistant to a common chemotherapy treatment. These results give us a strong incentive to con...
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