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Real Cause of Cancer

image Lifestyle factors are the most important cause of cancer, say scientists. Bernard Stewart, professor of oncology at the University of New South Wales, said: "Measures known to prevent cancer include smoking cessation, reducing alcohol intake, curbing obesity and avoiding deliberate sun exposure." "Diverting attention from these messages threatens to undermine their efficacy to deliver proven benefits," added Stewart, who systematically reviewed medical literature o...
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Nearly 1.3 Million Deaths from Cancer in the EU in 2012 Predicted by Researchers

image Nearly 1.3 million deaths from cancer in 2012 in the European Union (EU) - 717,398 men and 565,703 women have been estimated according to the new figures published today (Wednesday). Although the actual numbers have increased, the rate (age-standardised per 100,000 population) of people who die from the disease continues to decline. Writing in the cancer journal IAnnals of Oncology/I [1], a group of researchers from Italy and Switzerland estimate that the overall cancer death rat...
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Study Assesses Number of GP Visits Cancer Patients Make Before Being Referred to Specialists

image A recent study has revealed that nearly 77% of cancer patients are referred to specialists by their family doctors only after one or two consultations The study, led by researchers at the University of Cambridge, found that patients with breast, melanoma, testicular and endometrial cancers are more likely to be referred to a specialist after just one or two consultations. However, patients with some less common cancers such as multiple myeloma, pancreatic, stomach and ovarian cance...
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Route to New Therapeutic Scope in Cancer Treatment Via Mighty Tiny Move

image Vall d'Hebron Institute of Oncology (VHIO) guided study hails a new horizon in the battle against cancer, opening up a parallel dimension to treatment choices already available. The data, published today in the IJournal of Clinical Oncology/I, demonstrate that by combining two drugs that had already been used on a patient in the past but had stopped working, they boost each other's efficacy and at the same time manage to break down the patient's resistance to each of them individually, prese...
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Research: CT Colonography is Comparable to Standard Colonoscopy

image A new study suggests that computerized tomographic (CT) colonography (CTC) is comparable to standard colonoscopy in its ability to accurately detect cancer and precancerous polyps in people aged 65 and older. The paper is published online today in IRadiology/I. This is consistent with results of the ACRIN National CT colonography Trial, published in the INew England Journal of Medicine/I in 2008, which demonstrated CT colonography can serve as a primary colorectal cancer sc...
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Spread of Cancer can be Decreased by Combined Inhibition of Growth Factors

image New research indicates that dual inhibition of vascular endothelial growth factor and c-MET signaling inhibited tumor invasion and metastasis in a laboratory model of pancreatic neuroendocrine cancer. The paper is published in ICancer Discovery/I, the newest journal of the American Association for Cancer Research. "Inhibition of VEGF signaling plus c-MET signaling results in a synergistic effect on tumors that leads to slowing of tumor growth and decreased invasiveness and metast...
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Cancer Therapy Headier When Attacking 2 Targets

image Targeting two different molecules in cancer simultaneously is an effective way to shrink tumors, block invasion, and stop metastasis, scientists have found at the University of California, San Francisco (UCSF). The work may improve the effectiveness of combination treatments that include drugs like Avastin. The two-target approach, tested in mice with a type of cancer known as neuroendocrine pancreatic tumors, may have broad application for treating a wide variety of cancers, the UC...
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Scientists Identify Inflammatory Circuit Which Triggers Breast Cancer

image Scientists have been able to identify the Inflammatory circuit which triggers breast cancer. Now, scientists from the Florida campus of The Scripps Research Institute have shed new light on exactly how the activation of a pair of inflammatory signaling pathways leads to the transformation of normal breast cells to cancer cells. The scientists' discovery points to the activation of a self-sustaining signalling circuit that inhibits a specific RNA, a well-known tumour supp...
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Promise of New Drugs Thanks to Discovery on Cancer

image Researchers at the University of California, San Francisco (UCSF) have discovered how a protein "master regulator" dysfunctions leading to spread of cancer by uncovering the network of genes regulated by a crucial molecule involved in cancer called mTOR, which controls protein production inside cells. Their work also pinpoints why past drugs that target mTOR have failed in clinical trials, and suggests that a new class of drugs now in trials may be more effective for the lethal form ...
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How Cancer Cells Change Once They Spread to Other Areas in the Body

image Cancer cells must transform themselves so they can detach from a tumor before spreading to a distant organ. Now, scientists at Weill Cornell Medical College have revealed critical steps in what happens next -- how these cells reverse the process, morphing back into classical cancer that can now grow into a new tumor. Their findings, now published online and in a upcoming issue of ICancer Research/I and funded through a National Cancer Institute grant to the Cornell Ce...
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