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The Mechanics Behind New Breast Cancer Tumour Suppressor

image A recent study has identified a new breast cancer tumour suppressor protein that regulates the gene expression. Researchers from the Nagasaki University discovered that a significant proportion of mice, lacking one of two Runx3 genes spontaneously developed mammary gland tumours at 14 or 15 months of life. The age is equivalent to age 40 to 50 in human beings. "People suggested that Runx3 might be a tumour suppressor in breast cancer because they found that it...
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Brain Tumors Could be Treated With Novel Therapeutic Gene

image Scientists have developed novel tools and methods for delivering therapeutic genes to cells in the central nervous system that hold great promise for the development of new treatments to treat brain tumors and other neurological disorders. They have reported the successful use of stem cells derived from human umbilical cord blood to deliver a novel therapeutic gene-interleukin-12-to the brain for long-term anti-tumor activity against gliomas, a deadly type of brain tumor. ...
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Adult Tumor Risk Higher in Childhood Cancer Survivors

image In the largest study yet, it was found that childhood cancer survivors are at a high risk of developing new tumours as they age. The research involved 14,358 individuals enrolled in the federally funded Childhood Cancer Survivor Study (CCSS). St. Jude Children's Research Hospital investigators leading the effort reported that 1,382, or 9.6 percent, of survivors developed new tumours unrelated to their original cancers. About 30 percent of those survivors, 386 ...
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Personalizing Therapy for Women With Triple-Negative Breast Cancer Soon

image Researchers have identified six subtypes of an aggressive and difficult-to-treat form of breast cancer and identified chemotherapies to which the different subtypes respond in cultured cells and animal tumor models. Knowing the specific subtype could help physicians determine which therapies would work best in patients with triple-negative breast cancer and also inform the discovery and development of new drugs to treat this aggressive form of breast cancer, the authors suggest. ...
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Genetic Mutation That Occurs in Most Ovarian Cancers Identified

image A group of American researchers have identified a genetic mutation that occurs in majority of the ovarian cancer cases raising hopes of the possibility of the early detection of the disease. The researchers were part of The Cancer Genome Atlas project which was launched by the US National Cancer Institute and the US National Human Genome Research Institute back in 2006. The researchers analyzed 316 ovarian cancer tumors and found that almost 96 percent of the tumors exhibited ...
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Lung Cancer Deaths can be Reduced by Screening

image A new study published in the New England Journal of Medicine has suggested that screening all smokers or ex-smokers can reduce the number of deaths due to lung cancer by more than 20 percent. The decade long National Lung Screening Trial included more than 53,000 people and was funded by the National Cancer Institute. The researchers said that deaths by lung cancer can be prevented by the early detection of the disease though a number of health experts have questioned who shou...
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FDA Move Against Cancer Drug Avastin Appealed by Roche

image A two-day appeal asking the US Food and Drug Administration to allow the top-selling drug Avastin to be used for breast cancer has been initiated by Roche. The FDA decided in December that Avastin was not an effective treatment for breast cancer and said it would take steps to revoke market approval and change the drug's label. The US regulatory move followed the recommendation of an expert panel that said the drug, also known as bevacizumab, carries risks such as severe ...
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Sunshine and Breast Cancer

image Three hours a day cut the risk of developing breast cancer by half, reveals research. It is the latest in a series of studies that add to the already strong evidence that the 'sunshine vitamin' helps prevent cancer. The researchers at the University of Toronto found that being outdoors stimulates the production of the vitamin and exposure to sunlight for 21 hours a week between April and October significantly cuts the chances of developing a tumour, reports the Daily ...
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Magnetic Nanoparticles That Can Kill Cancer Cells Developed

image Nanoparticles that has the ability to kill the cancer cells under the influence of a magnetic field has been developed by South Korean scientists. The magnetic nanoparticles developed by a Yonsei University research team led by Professor Cheon Jin-woo can convert external magnetic energy into heat with a significant increase in the efficiency of magnetic thermal induction, English.news.cn reported. The team performed an anti tumour study in mice, and found that the t...
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Vitamin D Supplements may Reduce Melanoma Risk in Women

image A new study published in the Journal of Clinical Oncology has suggested that women who are at an increased risk of suffering from melanoma, the deadliest form of skin cancer, can reduce the risk by opting for commonly used vitamin D supplements. Researchers led by Dr Jean Tang of the Stanford University School of Medicine used data from the Women's Health Initiative study in which over 36,000 postmenopausal women over the age of 50 years took part. The researchers studied the ...
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